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Anaesthesia


Title:Lorazepam as a premedicant for day-case surgery: an assessment
Author(s):Loach, A. Fisher, A.
Address:
Year:1975 Jul
Journal Title:Anaesthesia
Page Number:545-9
Language:eng
Volume:30
Issue:4
ISSN/ISBN:0003-2409 (Print). 0003-2409 (Linking)
Abstract:The sedative effect of 2 mg of lorazepam was assessed in eleven patients undergoing minor "day case" surgery and the results compared with a control group of eleven patients receiving a placebo. Sedation was assessed by a scoring method and quantified in terms of change in plasma cortisol levels. The results indicate that 2 mg of oral lorazepam produces good sedation (superior to nitrazepam in terms of plasma cortisol reduction) and has a postoperative anti-emetic effect but its prolonged duration of action makes it unsuitable for patients returning home within 8 hours of premedication.

 
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